Signal and Noise

Interpreted

Signal and Noise is a podcast about the numbers that quietly shape modern medicine. Lab tests influence diagnoses, guide treatment decisions, and drive a surprising amount of confidence and anxiety. But the numbers don't explain themselves, and the story they tell isn't always the one people think they're hearing.

In each episode, Chris Zahner and Dr. Michael Laposata talk through how medical tests actually work, why results can be misleading, and how meaning gets lost when numbers are treated as answers instead of clues.

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What You'll Get From This Show

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Better Intuition

Develop a clearer understanding of how medical tests work

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Clearer Results

Know what lab results can and can't tell you

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Less Hype

More judgment, fewer oversimplified conclusions

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Great Conversations

Interesting even if you're not a clinician

About the Show

Signal and Noise explores the intersection of laboratory medicine and clinical decision-making. We unpack common assumptions, unexpected pitfalls, and the judgment calls that sit behind everyday medical decisions.

This show is for people who are curious about medicine, like understanding how things really work, and enjoy thoughtful conversations that cut through complexity without dumbing anything down.

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